Spain reported 37,467 gonorrhoea cases and 11,879 cases of syphilis in 2025, with both infections showing signs of stabilisation at high levels. Chlamydia continued to climb, reaching 44,511 cases.
Spain’s latest surveillance report counted 37,467 gonorrhoea cases in 2025, alongside 11,879 cases of syphilis. The figures remain high, but the rise in both infections has slowed. Chlamydia moved in the opposite direction: reported cases reached 44,511.
The report, published by the National Centre for Epidemiology at the Carlos III Health Institute (ISCIII), says gonorrhoea’s annual percentage change fell from 36% in 2020–2023 to 3.5% in 2023–2025. That points to a plateau after years of sharp growth. Spain recorded just over 2,000 cases at the start of the century; annual increases have been particularly marked since 2018.
Gonorrhoea’s national rate was 76 cases per 100,000 people. Catalonia and Madrid had the highest rates. The Basque Country was also among the regions most affected. Men accounted for 84% of cases, and the average age was 32. Rates were highest among people aged 25–34, followed by those aged 20–24. Seven cases were reported in newborns after mother-to-child transmission.
Syphilis reached 24 cases per 100,000 people. Its reported total has more than doubled since 2020, when there were about 5,500 cases. The annual increase has been large since 2016, averaging 13.5%. Men made up 87% of cases; the highest rates were among people aged 25–34. Catalonia and Madrid recorded the highest regional incidence.
Ten children under two were diagnosed with congenital syphilis, all in their first months of life. Seven were boys and three were girls. The report recorded 1,217 basic cases and 950 secondary cases; for 71% of notifications, the clinical stage was not recorded.
Chlamydia is now the most frequently reported of the three infections. Cases rose from about 7,000 in 2016 to 44,511 in 2025, an annual increase of 17.9% over that period. The rate was 90 per 100,000 people. Half of cases were in men, whose average age was 28; women had an average age of 24. The highest case shares were among people aged 25–34 and 20–24.
The report also counted 1,824 cases of lymphogranuloma venereum, caused by Chlamydia trachomatis L1-L3, across 18 autonomous communities. That total was more than triple the roughly 400 cases recorded in 2020. A separate regional report covered DANA insurance exposure in the Comunidad Valenciana and Región de Murcia; in the STI figures, the highest chlamydia rates were in Catalonia and the Basque Country. Navarra also recorded one of the highest rates.