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Deep tech spin-off companies in Spain surpass one thousand in one year

Catalonia vs. Madrid: Where Are Spain's Most Promising Tech Startups Born?

Spain now boasts more than 1,000 deep tech spin-offs. Catalonia and Madrid lead in the number of new startups. Biotechnology, IT, and medicine are the main growth sectors.

In 2025, Spain has seen a significant increase in the number of spin-off companies engaged in deep tech. According to recent data, there are 1,007 such firms operating in the country—up 3.6% from the previous year. These companies are founded within universities and research centers to bring scientific discoveries and technological innovations to the market.

The highest concentration of new companies is found in Catalonia and Madrid, which together account for more than half of all deep tech spin-offs in Spain. Catalonia leads with a 28.2% share, while Madrid follows with 23.7%. The top three is completed by the Valencian Community, home to 11.1% of such startups. Andalusia and the Basque Country are also showing dynamic growth, each with its own scientific and industrial strengths.

Technology sectors and the role of universities

More than half of all deep tech spin-offs in Spain focus on biotechnology, information technology, and healthcare. Biotech accounts for nearly 20% of the market, IT for 17.4%, and medical projects for 16.7%. Most new companies originate within universities, with public institutions playing a key role. Among the leaders in creating spin-offs are the Polytechnic University of Madrid, CSIC, the Polytechnic University of Catalonia, University of Alicante, and University of Santiago de Compostela.

The annual turnover of deep tech spin-off companies in Spain is estimated at 1.4 billion euros. The highest revenues come from projects in energy, Industry 4.0, and IT. These sectors also lead in job creation. In total, deep tech spin-offs employ over 13,400 specialists, with most positions in high-tech and knowledge-intensive fields.

Trends and prospects for development

Despite positive trends, the figures compared to last year are mixed. The previous study included not only active but also closed or inactive companies, which explains the difference in numbers. Now, only currently active firms are counted, providing a more accurate picture of the market.

The government continues to support the development of the deep tech ecosystem by investing in promising projects and startups. The focus is not only on funding but also on creating conditions for knowledge exchange, attracting investors, and drawing in talented professionals. Among the key priorities are biotechnology, energy, medicine, and robotics.

Spain on its way to European leadership

Experts note that the development of deep tech spin-offs is becoming a strategic factor in strengthening Spain’s position in the global technology market. The country is creating a favorable environment for the emergence of new companies based on scientific research and innovation. In the coming years, the number of startups is expected to continue growing, with closer collaboration with European partners for experience sharing, joint investments, and attracting new talent.

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