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Melanoma study identifies p38a as a target for stronger immunotherapy

Researchers in Barcelona identified p38a as a possible target in melanoma. Blocking the protein strengthened anti-PD-1 treatment in animal models and sometimes cleared tumours completely, but the findings remain preclinical.

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Melanoma target may improve immunotherapy response

A Vall d'Hebron study points to p38a as a possible melanoma treatment target. Blocking the protein improved anti-PD-1 therapy in animal models, while a nine-gene profile may help identify tumours more likely to respond.

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Venus hides a volcanic divide between its north and south

Venus has a thinner lithosphere in the north. That side also contains more than twice as many volcanoes. Researchers say the difference changes how the planet releases internal heat.

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Venus Reveals a North South Split in Its Rigid Outer Shell

A study of Venus found a thinner lithosphere and more than twice as many volcanoes in the north. The result adds a north-south divide to models of how the planet loses internal heat.

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European Solar Telescope Joins ESFRI Landmark Network

The European Solar Telescope now has ESFRI Landmark status. Spain leads the La Palma project, which will use a 4.2-metre mirror to study solar magnetic activity and space weather.

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Modern cars with emission faults outpollute well-kept classics

A technical report reveals that a small number of faulty modern vehicles are responsible for half of urban pollution, while many older cars remain clean if properly maintained. The findings question the fairness of age-based driving restrictions.

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Vall d'Hebron identifies a target linked to melanoma resistance

Vall d'Hebron researchers identified p38α as a possible target in melanoma treatment. Blocking the protein improved anti-PD-1 responses in experimental models and revealed a nine-gene signature linked to treatment outcomes.

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Vall d'Hebron study points to p38α in melanoma resistance

Researchers at Vall d’Hebron found that blocking p38α improved anti-PD-1 treatment in melanoma models. The work also identified a nine-gene signature linked to treatment response and survival.

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Manganese nanodots offer a safer route for MRI contrast

Spanish researchers have developed five-nanometre carbon nanodots with stable manganese. In rodent studies, the particles matched gadolinium contrast performance while showing fluorescence and good biocompatibility.

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Covid peaks shift toward late summer in Catalonia

A Catalan study of 30,000 PCR samples found Covid peaks in August and September. The pattern has reopened the debate over autumn vaccination timing, but researchers say more evidence is needed.

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Crew-13 reaches the ISS after a record US flight

Dragon reached the ISS in 7 hours 55 minutes, setting a US record for the fastest crewed flight to the station. Canadian astronaut Joshua Kutryk will remain in orbit when his wife gives birth to their third child.

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Why chronic pain affects twice as many women

A Science review examines why chronic pain affects women at roughly twice the rate of men. Hormones may shape pain sensitivity, immune responses and pain processing across the body.

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Depression diagnosis moves toward brain-based symptom profiles

Researchers at Barcelona's Instituto de Investigación Sant Pau are challenging the idea that depression has one biological pattern. Their review links symptoms such as anhedonia, rumination, insomnia and suicidal behaviour to different patterns of brain connectivity.

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Charlie tests Mars technology in Almería desert

Operations for the six-wheeled Charlie rover were run from Italy during trials in Spain's Tabernas desert. The campaign tests systems planned for ExoMars Rosalind Franklin, including navigation when Earth cannot respond at once.

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Sener nears final tests for Rosalind Franklin Mars landing gear

Sener is finishing the final qualification work on Rosalind Franklin's landing gear. The four-leg system must deploy in under one second before the 2028 mission begins its search for signs of life on Mars.

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Wilkes Basin Puts East Antarctica on the Climate Front Line

Scientists still lack basic ocean and seabed data from the Wilkes Subglacial Basin. The ice beneath East Antarctica could raise global sea levels by up to four metres.

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Sugar Intake During Antibiotics Threatens Cancer Patient Survival

A major study reveals that consuming sugar while on antibiotics can sharply worsen gut microbiome loss in cancer patients, raising their risk of life-threatening complications. The findings challenge current hospital nutrition practices and highlight a critical, modifiable risk factor.

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Cancer care now asks how patients live after treatment

Spanish oncologists are looking past survival alone. At its Madrid congress, SEOM is calling for care that helps patients rebuild daily life while precision medicine reshapes treatment.

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MSD Animal Health launches Nobivac NXT in Spain

MSD Animal Health presented Nobivac NXT at its Madrid headquarters, where more than 110 distribution partners attended the first launch meeting. The company is entering a market in which around one in five cats still does not receive vaccination.

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Barcelona children get a hands-on route through the universe

A free astronomy workshop will take place in Sarrià on 28 October. Children aged 9 to 12 will explore stars and galaxies, then make a galaxy to take home.

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CNIO identifies a weak stage before brain metastases cause symptoms

A six-year CNIO study found a short period when early brain metastases become vulnerable. Three drugs eliminated micrometastases in mice and human tissue before visible tumours formed.

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Almería puts Mars landing gear through its final test

A Spanish-built landing system is entering its final qualification stage. ESA will test a Mars rover prototype in Almería before the 2028 mission.

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CNIO identifies a brief window to attack hidden brain metastases

CNIO researchers found a short stage when early brain metastases are unusually vulnerable. Three drugs removed micrometastases in animal models before they developed into detectable tumours.

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CNIO finds a drug window against hidden brain metastases

CNIO researchers have identified a vulnerable stage in early brain metastases. Three drugs eliminated microscopic lesions in mice and human tissue before they became clinically detectable, opening a possible route to preventing recurrence.

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Blood test opens a new route to personalised cancer therapy

VHIO researchers found tumour neoantigens and responsive T cells in blood samples. The method could widen access to personalised immunotherapy when tumours are hard to biopsy.

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Global flu surveillance becomes Spain's early warning system

Spain's flu activity is still low, but early changes are appearing among younger people. Álvaro Torres explains why international surveillance helps track variants and plan prevention before the next season takes shape.

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CNIO finds a vulnerable window against brain metastasis

Spanish researchers found a brief stage when early brain metastases may respond to treatment. Three drugs cleared microscopic lesions in mice and human tissue, but clinical trials are still needed.

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CNIO finds a drug target in early brain metastases

CNIO researchers found a short period when early brain metastases are unusually vulnerable. Three drugs destroyed micrometastases in laboratory models before they became detectable tumours.

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A Four-Carbon Sugar Has Been Found in the Milky Way

Researchers have detected erythrulose in a Milky Way molecular cloud. The result shows that space can supply carbohydrates for chemical reactions linked to the origins of life.

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Starship sets up its first full orbit around Earth

SpaceX is preparing Starship's fourteenth test flight for Monday, September 28, 2026. The mission could last 10 hours, circle Earth six times and test a controlled return while deploying 26 Starlink V3 satellites.

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Human Brain's Cellular Patterns Shift Around Age 24

A new atlas tracks brain changes from childhood to age 97. Most cell populations in the prefrontal cortex settle into relative stability around 24, then molecular activity rises again in later life.

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Iberian Peninsula Builds Early Warning System for Canine Leishmaniosis

A new data system will monitor canine leishmaniosis across the Iberian Peninsula. It combines climate records, sand fly surveillance and veterinary diagnoses to forecast where risk may rise.

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Spain Builds Early Warning System for Canine Leishmaniosis

A European project is designing an early warning system for Spain and Portugal. It will combine climate data with veterinary and public health records to support earlier action against canine leishmaniosis.

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Super El Niño Could Put 451000 Lives at Risk

El Niño may bring its deadliest heat in decades. Spain could record 480 additional deaths, with Madrid, Andalusia and Catalonia facing the greatest risk.

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Progesterone May Change How the Brain Reads Emotion

A University of Barcelona study links higher progesterone with less precise emotional processing and lower mood. The findings could help shape more personal care for hormone-related mood disorders.

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